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Country/Region:United States
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Creative Bioarray
We are professional supplier of cells,tissue,sample.
Business Type:Manufacturer
Country/Region:United States
Ddu Verified
HOT Rank
6/10
The chemoattractant-homologous receptor expressed on TH2 cells (CRTH2, also known as DP2 and GPR44) serves as a receptor for prostaglandin D2 (PGD2) and has been reported to mediate PGD2-dependent migration of eosinophils. DP2 mediates the pro-inflammatory effects of PGD2 generated in allergic inflammation. 11-Dehydrothromboxane B2 (11-dehydro-TXB2) was found to be a full agonist of the DP2 receptor and hence might cause the receptor activation in cellular contexts where PGD-synthase is not present. Antagonism of the 11-dehydro-TXB2/DP2 axis may be of therapeutic relevance.
https://acroscell.creative-bioarray.com/human-ptgdr2-apoaequorin-stable-cell-line-cho-acc-rg1326-item-812.htm