Human CALCRL+RAMP3/beta-Arrestin Stable Cell Line-CHO- Creative Bioarray

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Human CALCRL+RAMP3/beta-Arrestin Stable Cell Line-CHO

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Creative Bioarray

Business Type:Manufacturer

Country/Region:United States

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8/10

Product Information

Certification:CE
Brand Name:Creative Bioarray
Trademark:Creative Bioarray
Place of Origin:Shirley
Warranty:1 year

Description

The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP3) protein, CRLR functions as an adrenomedullin receptor.

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